Post by jeffolie on May 31, 2011 12:28:47 GMT -6
med forced 'Healthy' Cholesteral (HDL) fails to improve life spans
Health Nazis
Health Nazis demand you change your life, take meds, comply with orders.
Are you worried about your 'numbers'? Are you stressed and forced into unhappy lifestyles and living by domineering Health Nazis?
Health Nazis maybe doctors, nurses, peers, snake oil sellers of homopathic supplements.
Often the demands change over time such as the food pryamid requiring what types of foods are good, bad and ugly.
Below the Health Nazis demanded taking meds re cholesteral, a certain type of 'Healthy' cholestral was required and ordered.
Now, the 'Healthy' cholestral drugs tested and studied did not improve outcomes...life spans did not increase.
The same 'life spans did not increase' result came from Health Nazis demands and orders to get diabetics sugar levels, A1c, below a certain number...in fact deaths happened.
Health Nazis should reframe from demands and orders not backed up by studies that prove better outcomes such as living longer or improving general life abilities and/or functions.
Below, the med forced up HDLs and failed to improve life spans or living better. Higher HDL have been associated with benefits but forcing up HDLs with meds failed...the cause and effect was not proven before the Health Nazis demanded taking this med...similar results for Zetia forced on people by dominating Health Nazis and by Big Pharma wants profits regardless if money is wasted on worthless meds.
I limit my health and medical exposure to M.D.s, doctors that are open to listening my own internet research...I avoid close minded, domineering Health Nazis that are not M.D.s, doctors that do not keep current on large, broad studies on humans.
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NIH halts niacin-and-statin trial early
A trial of niacin and statins was halted 18 months early after no signs were seen that niacin reduced the risk of heart attack or stroke. Niacin is often prescribed to boost HDL levels. (Ricardo DeAratanha / Los Angeles Times)
May 27, 2011
Small studies had hinted that large doses of niacin might help prevent heart attack or stroke, and hopes were high that this might prove to be the case. Now those hopes appear dashed. The NIH has stopped a trial 18 months ahead of schedule after finding that combining extended-release, high-dose niacin with a statin doesn’t seem to reduce the risk of such cardiovascular events.
Niacin, or vitamin B3, is often taken to help reduce blood levels of triglycerides and LDL, the so-called bad cholesterol, and to boost levels of HDL, the so-called good cholesterol. And statins, of course, are drugs used to treat high cholesterol by limiting the body’s production of it.
It made sense to try to team them up, especially for people who already had low LDL (courtesy of a statin) but who were nonetheless at risk because of their history of cardiovascular disease and their low HDL levels and high triglyceride levels.
In the now-halted trial, 3,414 people took simvastatin (Zocor), and some also took a second cholesterol-lowering drug, ezetimibe (Zetia), to ensure that LDL levels remained low. About half of the participants also received a high daily dose of extended-release niacin.
Overall, those in the niacin group did have increased HDL levels and lowered triglyceride levels after 32 months, the researchers found, but they were no less likely to suffer heart attacks, strokes or be hospitalized for acute coronary syndrome.
In fact, a few more people in the niacin group experienced ischemic strokes, in which a clot blocks blood to the brain—one reason the trial was stopped early, according an announcement Thursday from the National Heart, Lung, and Blood Institute.
From the institute’s statement:
"The lack of effect on cardiovascular events is unexpected and a striking contrast to the results of previous trials and observational studies," said Jeffrey Probstfield, co-principal investigator and professor of medicine and epidemiology at the University of Washington, Seattle.
Researchers will now begin examining their data in considerable detail. In the meantime, consumers might do well to read up on statins, lifestyle changes and niacin itself.
www.latimes.com/health/boostershots/la-heb-niacin-heart-20110527,0,1707473.story
Health Nazis
Health Nazis demand you change your life, take meds, comply with orders.
Are you worried about your 'numbers'? Are you stressed and forced into unhappy lifestyles and living by domineering Health Nazis?
Health Nazis maybe doctors, nurses, peers, snake oil sellers of homopathic supplements.
Often the demands change over time such as the food pryamid requiring what types of foods are good, bad and ugly.
Below the Health Nazis demanded taking meds re cholesteral, a certain type of 'Healthy' cholestral was required and ordered.
Now, the 'Healthy' cholestral drugs tested and studied did not improve outcomes...life spans did not increase.
The same 'life spans did not increase' result came from Health Nazis demands and orders to get diabetics sugar levels, A1c, below a certain number...in fact deaths happened.
Health Nazis should reframe from demands and orders not backed up by studies that prove better outcomes such as living longer or improving general life abilities and/or functions.
Below, the med forced up HDLs and failed to improve life spans or living better. Higher HDL have been associated with benefits but forcing up HDLs with meds failed...the cause and effect was not proven before the Health Nazis demanded taking this med...similar results for Zetia forced on people by dominating Health Nazis and by Big Pharma wants profits regardless if money is wasted on worthless meds.
I limit my health and medical exposure to M.D.s, doctors that are open to listening my own internet research...I avoid close minded, domineering Health Nazis that are not M.D.s, doctors that do not keep current on large, broad studies on humans.
====================================================
NIH halts niacin-and-statin trial early
A trial of niacin and statins was halted 18 months early after no signs were seen that niacin reduced the risk of heart attack or stroke. Niacin is often prescribed to boost HDL levels. (Ricardo DeAratanha / Los Angeles Times)
May 27, 2011
Small studies had hinted that large doses of niacin might help prevent heart attack or stroke, and hopes were high that this might prove to be the case. Now those hopes appear dashed. The NIH has stopped a trial 18 months ahead of schedule after finding that combining extended-release, high-dose niacin with a statin doesn’t seem to reduce the risk of such cardiovascular events.
Niacin, or vitamin B3, is often taken to help reduce blood levels of triglycerides and LDL, the so-called bad cholesterol, and to boost levels of HDL, the so-called good cholesterol. And statins, of course, are drugs used to treat high cholesterol by limiting the body’s production of it.
It made sense to try to team them up, especially for people who already had low LDL (courtesy of a statin) but who were nonetheless at risk because of their history of cardiovascular disease and their low HDL levels and high triglyceride levels.
In the now-halted trial, 3,414 people took simvastatin (Zocor), and some also took a second cholesterol-lowering drug, ezetimibe (Zetia), to ensure that LDL levels remained low. About half of the participants also received a high daily dose of extended-release niacin.
Overall, those in the niacin group did have increased HDL levels and lowered triglyceride levels after 32 months, the researchers found, but they were no less likely to suffer heart attacks, strokes or be hospitalized for acute coronary syndrome.
In fact, a few more people in the niacin group experienced ischemic strokes, in which a clot blocks blood to the brain—one reason the trial was stopped early, according an announcement Thursday from the National Heart, Lung, and Blood Institute.
From the institute’s statement:
"The lack of effect on cardiovascular events is unexpected and a striking contrast to the results of previous trials and observational studies," said Jeffrey Probstfield, co-principal investigator and professor of medicine and epidemiology at the University of Washington, Seattle.
Researchers will now begin examining their data in considerable detail. In the meantime, consumers might do well to read up on statins, lifestyle changes and niacin itself.
www.latimes.com/health/boostershots/la-heb-niacin-heart-20110527,0,1707473.story